Daniella Owusuwaah

BIOS 5860

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January 29th 2018

5 Important Concepts and Muddiest Points

 

1.    
The
innate immune system is present at birth, it’s fast, lacks specificity, and memory;
and as a result does not improve with each pathogen encounter.  

2.    
The
first line of defense for innate immunity: is the skin which is typically
impermeable and the mucous membrane that prevents bacteria from sticking to the
epithelial cells, and entering the body.

3.    
Pathogens
compete with the normal microbiota for nutrients making it a great defense,
however any break in this defense allows for opportunistic pathogens to
infiltrate and cause harm.

4.    
Antimicrobial
peptides (AMP) are small amphipathic proteins that are essentially for fighting
an infection, however they must be activated in order to be cleaved and released.

5.    
Interferons
are cytokines that are produced to inhibit the spread of a virus by signaling neighboring
cells to enter a viral resistance state.

 

Muddies Points

 

Defensins  and APOBEC3G